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    But on June 12, Daleyza Hernandez Avila, 3, died during a dental procedure.The dentist sedated Daleyza to keep the toddler from wriggling while she was getting crowns and having a tooth pulled. Now, Araceli wants to warn other parents about the dangers that she wasn’t aware of.Diazepam, the current anticonvulsant of choice in the management of OP poisoning, is associated with unwanted effects such as sedation, amnesia, cardio-respiratory depression, anticonvulsant tolerance, and dependence liabilities.In search for an efficacious and safer anticonvulsant benzodiazepine, we studied imidazenil, a potent anticonvulsant that is devoid of sedative action and has a low intrinsic efficacy at α1- but is a high efficacy positive allosteric modulator at α5-containing GABA receptors.But carfentanil is just one part of the far bigger issue of painkiller use and abuse.Araceli Avila never dreamed that her daughter's life might be at risk during a visit to the dentist.Wendy Sue Swanson of Seattle Children's Hospital and a spokesperson from the influential pediatricians group is sounding the alarm about sedating children for oral surgery."If we can prevent one more child from an adverse event or a death, we’ve got to try,” Swanson told NBC News. The state boards that oversee dental practice in America usually don’t make that kind of information public.

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    Unfortunately, dental anxiety can have negative effects on patients’ oral health.

    Those incredibly nervous about dental treatment need something more than mere anesthesia.

    IV sedation provides patients with a sedative medication for the duration of treatment.

    While it is often called “sleep sedation,” IV sedation does not place patients in an unconscious state the way general anesthesia does.

    Fentanyl, the opioid painkiller that killed Prince and is 50 times stronger than morphine, pales in comparison to a new drug called carfentanil.

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